OVERCOMING CHALLENGES TO ENABLE TARGETING OF METASTATIC BREAST CANCER TUMOUR MICROENVIRONMENT WITH NANO-THERAPEUTICS: CURRENT STATUS AND FUTURE PERSPECTIVES

Tumour-microenvironment (TME) comprising of impenetrable inter-communications among stromal cells, tumour cells, cancer-associated blood and lymphatic vessels, pericytes, cancer-associated-fibroblasts, cancer-stem cells and multimatic 255 tig kit extracellular matrix (ECM) that can substantially impact the onset, spread and progression of cancer me

In this paper, we proposed a contrast-enhanced homemade spectral domain optical coherence tomography (SD-OCT) method for monitoring of brain microcirculation.We used the polyethylene glycol (PEG)-ylated gold nanorods (GNRs) traditional bull pinata as a contrast-enhanced agent, obtained clearly 2D and 3D OCT images of blood vessels and dynamic chang

One reason of the modest adoption of improved technologies by smallholder farmers is that the majority of them are resource constrained.Structural constraints at the households level and institutional weaknesses have often prevented most of the farmers from joining the economic development process.This study analyses the production resources in rel

A new multiarc sprag clutch model considering geometry and internal interaction during engagement is proposed in this paper.To increase the accuracy of the model, an improved model of geometric deformation coordination is presented to describe the basic geometrical quantities after rotation of the sprag.Then, based on this model, a novel nonlinear